After placebo run – in, patients were started on amlodipine 5 mg and were titrated at three week intervals if mean cuff BP was greater than or equal to 120/80 mm Hg to AML / olmesartan medoxomil 20. AML / OM 5 /40 mg then AML / OM 10/40 mg. When BP was less than 120/80 mm Hg, patients were not titrated to the next dose and remained on the assigned dose . Twenty-four hours was performed ABPM at the beginning and end of the study . A total of 134 patients to to AML / OM 10/40 mg.
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