In developed countries, the good reasons are unclear why stillbirths occur often, and surveillance and autopsy data are patchy. For the Bakers, leaving the hospital after their daughter arrived lifeless was the hardest component. They spent a long time with baby Scarlett after she in December 2009 was born. Nobody ever really wants to talk about because it’s therefore sad, she said. But three weeks ago, her tragedy acquired a happier ending. Baker offered birth to a child, Harry. She and her spouse also have an older daughter, Sydney. The entire stillbirth report are available at The Lancet. .. American stillbirths: How many babies die? LONDON – Don’t assume all pregnancy ends happily. Those are the terms of Samantha Baker, a British accountant near London who gave birth to a stillborn daughter she called Samantha.Researchers believe that, in cells without BRCA1, 53BP1 spurs excessive NHEJ that may trigger fatal chromosomal chaos. But with 53BP1 taken care of, the cells can easily resume homologous recombination. That may clarify why cells that absence BRCA1 and eliminate 53BP1 can withstand traditional chemotherapy substances and PARP inhibitors, a fresh generation of anti-ckancer medications that are in scientific trials. But just how do tumor cells ignore 53BP1? Researchers previously discovered that particular mutant fibroblasts increase creation of cathepsin L, a protease that destroys 53BP1.